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DNA POLYMERASE FOR DNA SEQUENCING WITH MODIFIED NUCLEOTIDE BONDING SITE
DNA POLYMERASE FOR DNA SEQUENCING WITH MODIFIED NUCLEOTIDE BONDING SITE
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机译:DNA聚合酶与修饰的核苷酸结合位点进行DNA测序
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摘要
DNA polymerases are provided which do not discriminate significantly against incorporation of a dideoxynucleotide compared to a deoxynucleotide. DNA polymerases having a reduced discrimination against dideoxynucleotides may be obtained by modifying the nucleotide binding site of a wild type DNA polymerase. The DNA polymerases are particularly useful for DNA sequencing. IMAGE
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