Method for early detection of sepsis, measurement of severity, and evaluation of sepsis course associated with treatment, and means for implementing the method

摘要

PCT No. PCT/EP93/02245 Sec. 371 Date Apr. 17, 1995 Sec. 102(e) Date Apr. 17, 1995 PCT Filed Aug. 19, 1993 PCT Pub. No. WO94/04927 PCT Pub. Date Mar. 3, 1994Disclosed is a method for early detection, detection of the severity as well as for a treatment-accompanying assessment of the course of a sepsis as well as means for carrying out said method. According to the invention, the content of the peptide procalcitonin and/or of a partial peptide formed therefrom which is not the mature calcitonin is determined in a sample of a biological liquid of a patient. From the determined presence and amount of the certain peptide, a conclusion is made about the presence of a sepsis, its severity and/or the success of a therapeutic treatment.