WATER-BASED PHARMACEUTICAL PREPARATION OF 9-METHYL-3-(1 H-TETRAZOL-5-YL)-4H-PYRIDO (1,2-A)PYRIMIDIN-4-ONE

摘要

PURPOSE: To obtain a water-based pharmaceutical preparation causing no crystal deposition even after preserved for a long period, highly excellent in preservability because of causing no TBX decomposition and being stable in pH level, thus esp. useful when used as a nasal drop, eye drop or liniment. ;CONSTITUTION: This water-based pharmaceutical preparation contains, as active ingredient, 9-methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a] pyrimidin-4-one or a physiologically permissible salt thereof {except those containing 0.05-0.5% (W/ V) of 9-methyl-3-(1H-tetrazol-5-yl)-4H-pyrido[1,2-a]pyrimidin-4-one potassium salt, 0.1-0.5% (W/V) of potassium hydrogenphosphate and 0.005-0.2% (W/V) of potassium dihydrogenphosphate}.;COPYRIGHT: (C)1996,JPO