NEW PEPTIDE, PRODUCTION THEREOF, DNA CODING PEPTIDE THEREOF, VECTOR COMPRISING THE GENE, HOST CELLS TRANSFORMED WITH THE VECTOR, ANTIBODY TO THE PEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING THE PEPTIDE OR ANTIBODY

摘要

PURPOSE:To provide a novel polypeptide which is produced from a human glioblastoma cell strain and has a specific amino acid sequence, thus is useful in treatment for diseases relating to growth insufficiency and anomaly proliferation of glia, neuron or hematopoietic cells or hyperergasia or hypergasia of nerve functions. CONSTITUTION:This polypeptide has a substantially pure form of amino acid sequence given in the formula or its homologues, its fragments and fragment homologues. The peptide is obtained by culturing a host cell transformed with an expression vector comprising the DNA coding the polypeptide under such conditions that the polypeptide is expressed. The dose of the polypeptide is preferably 100mum-100mg/single dose/adult.