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Bioactive conjugate and processes for covalent coating of implants with a bioactive conjugate and for cleaning a metal implant surface from contaminants
Bioactive conjugate and processes for covalent coating of implants with a bioactive conjugate and for cleaning a metal implant surface from contaminants
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机译:生物活性缀合物以及用生物活性缀合物共价涂覆植入物并清洁金属植入物表面上的污染物的方法
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摘要
The present invention relates to a bioactive conjugate adapted to coat a metal implant outer surface, which have the following structural formula (I): -R-X-P wherein, R is O or S, adapted to be covalently attached to an implant surface; X is selected from a bond, linear or branched chains of 1 to 30 covalently attached atoms of at least C, N, O, Si or S, rings of 1 to 20 covalently attached atoms of at least C, N, O, Si or S, and a combination thereof; and P is a bioactive molecular moiety which promotes tissue growth, stabilization and integration, and wherein said moiety retains its biological activity. The present invention also relates to a process for the covalent coating of implants with bioactive conjugates.
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