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THE USE OF A HIDDEN ANTIGEN OF INTESTINAL WORMS FOR PREPARING A VACCINE AND STIMULATION METHOD OF IMMUNITY RESPONSE
THE USE OF A HIDDEN ANTIGEN OF INTESTINAL WORMS FOR PREPARING A VACCINE AND STIMULATION METHOD OF IMMUNITY RESPONSE
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机译:肠道蠕虫隐藏抗原在制备疫苗中的作用及免疫反应的刺激方法
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摘要
The invention provides a use of a helminth hidden antigen, or antigenic fragments, precursors and functionally-equivalent derivatives or variants thereof having immunogenic activity against one or more helminth parasites, in the manufacture of a vaccine composition for administration to an animal at least once prior to and/or during a period of loss or warning of natural immunity to gastro-intestinal helminth parasites, whereby to stimulate protective immunity against said helminth parasites during the period of compromised natural immunity. The invention has particular utility in the control of the periparturient rise of the helminth nematode Haemonchus in sheep, and of type II ostertagiasis.
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