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MODIFIED ANTIVIRAL RIBOZYME AND ITS USE IN PREPARING VIRUS-RESISTANT PLANTS
MODIFIED ANTIVIRAL RIBOZYME AND ITS USE IN PREPARING VIRUS-RESISTANT PLANTS
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机译:修饰的抗病毒核酶及其在制备抗病毒植物中的用途
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摘要
Modified ribozymes comprise: (a) nucleolytically active RNA sequences capable of cleaving viral genomic RNA, mRNA or hnRNA and (b) satellite viruses or satellite RNA functionally linked with the nucleolytically active RNA sequences. Also claimed are: (1) a process for producing modified ribozymes, comprising functionally linking nucleolytically active RNA sequences as above with satellite viruses or satellite RNA; (2) a process for producing virus-resistant plants, comprising (a) transforming plant cells with DNA coding for the (sic) enzymatic RNA mols., (b) stably integrating the DNA into the plant genome, and (c) regenerating plants from these cells; and (3) DNA fragments coding for the modified ribozymes as above. IMAGE
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