Benzalkonium fluoride injectable solution and application as an antiviral or anti-infectious agent

摘要

PCT No. PCT/FR95/00070 Sec. 371 Date Oct. 22, 1996 Sec. 102(e) Date Oct. 22, 1996 PCT Filed Jan. 23, 1995 PCT Pub. No. WO95/19766 PCT Pub. Date Jul. 27, 1995Solution administrable by intravascular injection in a human or an animal which comprises an effective amount up to 0.23% by weight of a benzalkonium fluoride having the formula: IMAGE where R is an alkyl radical which may vary between C8H17 and C18H37, dissolved in an excipient injectable intravascularly. Preferably R is between C12H25 and C14H29, and more preferably C14H29. The solution can be packaged in 10 ml ampoules, containing about 21 mg of benzalkonium fluoride, the benzalkonium fluoride being dissolved in a physiological solvent. The solution also contains at least one metallic derivative of fluorine, preferably lithium fluoride.