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VACCINE WHOSE CHARACTERISTIC EPITOPE IS INCORPORATED IN A PICORNAVIRUS PROTEIN, IN PARTICULAR POLIOVIRUS.
VACCINE WHOSE CHARACTERISTIC EPITOPE IS INCORPORATED IN A PICORNAVIRUS PROTEIN, IN PARTICULAR POLIOVIRUS.
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机译:具有特征性表位的疫苗包含在特定的脊髓灰质炎病毒中。
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摘要
The invention relates to an active principle of a vaccine whose characteristic epitope is incorporated in the capsid of a picoravirus, in particular, the poliovirus, which serves as the vector. This active principle consists of a viable picornavirus hybrid containing an epitope which is characteristic of a vaccinating protein and is heterologous in respect of the proteins of said picornavirus, instead of one of its own immunogenic epitopes.
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