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Enantioselective synthesis of cyclic amino alcohols
Enantioselective synthesis of cyclic amino alcohols
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机译:环状氨基醇的对映选择性合成
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摘要
There is disclosed a novel process for the enantioselective synthesis of chiral amino alcohols from keto oxime ethers, which are derived from cyclic ketones, via catalytic asymmetric reduction, employing oxazaborolidine-borane complex (OAB-BH3). In this catalytic reduction process two chiral centers are created in a single step with high levels of stereoselectivity.
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