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EXPANSION OF STEM CELLS IN LONG TERM BONE MARROW CULTURES BY NEUTRALIZATION OF TGF-$g(b)
EXPANSION OF STEM CELLS IN LONG TERM BONE MARROW CULTURES BY NEUTRALIZATION OF TGF-$g(b)
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机译:TGF- $ g(b)的中和扩增长期骨髓培养的干细胞
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摘要
A method for expanding growth of hematopoietic stem cells in culture includes a step of admixing to the culture a TGF- beta antagonist such as a soluble TGF- beta receptor or a TGF- beta -neutralizing antibody. Also, treating an animal includes steps of admixing a TGF- beta antagonist to a culture of bone marrow cells to stimulate production of hematopoietic stem cells in the culture, and thereafter administering hematopoietic cells so produced to the animal. Also, a method for treating an animal includes steps of administering a TGF- beta antagonist to the animal.
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