MONOCLONAL ANTIBODIES AGAINST LEUKOCYTE-SPECIFIC G-PROTEIN-COUPLED RECEPTORS

摘要

the invention relates to monoclonal antibodies against leukocyte specific g protein coupled receptors (l (gcr).these antibodies are available through the following steps: $a (a) introduction of a l - gcr codon present in cells and expression of l - gcr, $a (b) immunization of an animal with l - gcr - exprimierenden cells of (a) and (c) $a fusion of spleen cells of the immunized animal of b ) with myeloma cells and maintenance of monoclonal gcr antibodies producing l - contaminate.the invention also relates to $a processes for producing such antibodies, their use and kits containing them. the invention also relates to processes for the manufacture of monoclonal gcr antibodies.