Preparation of sustained-release pellet formulations of diltiazem

摘要

The present invention relates to a pellet-type pharmaceutical formulation containing a giltiazem and / or a diltiazem hydrochloride (hereinafter referred to as diltiazem) and capable of being taken once a day by membrane coating And a method for manufacturing the same. That is, the present invention relates to a useful method for producing diltiazem sustained-release pellets having a release-controlling ability similar to a general organic solvent coating with a water-based membrane coating having a specific composition.