Mutant yeast in which cell wall is weakened by inactivating knr4 gene and production method of recombinant protein using the mutant yeast

摘要

The present invention relates to a mutant yeast in which a cell wall is weakened by inactivating a knr4 gene on a yeast genome DNA by a one step gene disruption method and an improved production method of a useful recombinant protein using the mutant yeast.