METHOD FOR MAKING DIFFERENTIAL DIAGNOSIS OF SUBLEUKEMIC MYELOSIS AND TRUE POLYCYTHEMIA

摘要

FIELD: medicine. SUBSTANCE: method involves taking peripheral patient blood to prepare smears, which are fixed, washed, dried, and applying incubation mixture. Then the preparation is repeatedly washed, dried and examined under microscope. Myeloperoxydase, nicotinamide adenine dinucleotide oxydase activity and cation proteins contents in neutrophils are determined. Total cytochemical activity is calculated for absolute number of segmented neutrophils. The value being equal to 10.3 or less, subleukemic myelosis is diagnosed. The value being equal to 10.3 or higher, true polycythemia is diagnosed. EFFECT: enhanced accuracy of differential diagnosis.