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SYNTHETIC PEPTIDES FOR VACCINE AGAINST GERMAN MEASLES

机译:预防德国麻疹疫苗的合成肽

摘要

FIELD: pharmacy, peptides. SUBSTANCE: synthetic peptides containing amino acid sequence corresponding at least to a single antigenic determinant, at least a single protein, usually structural one, especially E1-, E2- or C-protein, of German measles were used per se in hybrid or chimeric tandem in T-B-form, in modified lipid form associated with carrier molecule and/or polymerized up to preparing molecular aggregates in vaccines against German measles. Analogous peptides that are determinants of human T-cells were used for treatment autoimmune diseases associated with German measles. EFFECT: enhanced effectiveness of vaccine.
机译:领域:药学,多肽。物质:以杂交或嵌合串联的方式,使用了含有至少对应于单个抗原决定簇,至少单个蛋白(通常是德国麻疹的结构蛋白,尤其是E1,E2或C蛋白)的氨基酸序列的合成肽以TB形式,以修饰脂质形式与载体分子结合和/或聚合以制备针对德国麻疹的疫苗中的分子聚集体。人类T细胞决定簇的类似肽被用于治疗与德国麻疹有关的自身免疫性疾病。效果:提高疫苗效力。

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