where n = 0, 1 or 2; m = 0 or 1; each of Y and W means amino acid residue; R1 means hydrogen atom, C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkynyl, aryl, C1-C3-alkylaryl or C1-C3-alkylheteroaryl and -(CH2)pR3; R2 means CF3, C3-C6-alkyl, aryl, C1-C3-alkylaryl and -OR5; R3 means cyano-group, trifluoromethyl group or -OR4; R4 means C1-C6-alkyl, C1-C3-alkylaryl or aryl; R5 means C1-C6-alkyl, C1-C3-alkylaryl or aryl; R6 means hydrogen atom, -OR7 or NHCOR7; R7 means hydrogen atom, C1-C6-alkyl, aryl or C1-C3-alkylaryl; p = 1, 2 or 3 and above indicated aryl groups and aryl moieties in above indicated alkylaryl groups were taken independently from phenyl or substituted phenyl where above mentioned substituted phenyl can be substituted with one or three groups taken from C1-C4-alkyl, halogen atom (fluorine, chlorine, bromine or iodine), hydroxy-group, cyano-group, carboxamide, nitro-group and C1-C4-alkoxy-group, and their pharmaceutically acceptable salts. Synthesized compounds can be used in psychiatry, neurology, cardiology and some other branches of medicine. EFFECT: improved method of synthesis."/>
DERIVATIVES OF ACYLAMINOINDOLE AS 5-HTI-AGONISTS, PHARMACEUTICAL COMPOSITION AND TREATMENT METHOD
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DERIVATIVES OF ACYLAMINOINDOLE AS 5-HTI-AGONISTS, PHARMACEUTICAL COMPOSITION AND TREATMENT METHOD
DERIVATIVES OF ACYLAMINOINDOLE AS 5-HTI-AGONISTS, PHARMACEUTICAL COMPOSITION AND TREATMENT METHOD
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机译：乙酰氨基吲哚衍生物作为5-HTI激动剂，药物成分和治疗方法
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FIELD: organic chemistry. SUBSTANCE: product: compounds of the formula (I) where n = 0, 1 or 2; m = 0 or 1; each of Y and W means amino acid residue; R1 means hydrogen atom, C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkynyl, aryl, C1-C3-alkylaryl or C1-C3-alkylheteroaryl and -(CH2)pR3; R2 means CF3, C3-C6-alkyl, aryl, C1-C3-alkylaryl and -OR5; R3 means cyano-group, trifluoromethyl group or -OR4; R4 means C1-C6-alkyl, C1-C3-alkylaryl or aryl; R5 means C1-C6-alkyl, C1-C3-alkylaryl or aryl; R6 means hydrogen atom, -OR7 or NHCOR7; R7 means hydrogen atom, C1-C6-alkyl, aryl or C1-C3-alkylaryl; p = 1, 2 or 3 and above indicated aryl groups and aryl moieties in above indicated alkylaryl groups were taken independently from phenyl or substituted phenyl where above mentioned substituted phenyl can be substituted with one or three groups taken from C1-C4-alkyl, halogen atom (fluorine, chlorine, bromine or iodine), hydroxy-group, cyano-group, carboxamide, nitro-group and C1-C4-alkoxy-group, and their pharmaceutically acceptable salts. Synthesized compounds can be used in psychiatry, neurology, cardiology and some other branches of medicine. EFFECT: improved method of synthesis.
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