3-(PIPERIDINOCARBONYLMETHYLTHIO)-1,2,4-TRIAZINO-5,6-B-INDOLE SHOWING ANTIHYPOXIC ACTIVITY AND PROTECTING AGAINST ACUTE TOXIC LUNG EDEMA

摘要

FIELD: organic chemistry, heterocyclic compounds. SUBSTANCE: product: 3-(piperidinocarbonylmethylthio)-1,2,4-triazino-[5,6-b]-indole. Synthesis is carried out by reaction of 3-mercapto-1,2,4-triazino-[5,6-b]-indole in sodium hydroxide aqueous solution with 1-(chloroacetyl)-piperidine. Yield is 75%, m. p. is 222 C, empirical formula is C₁₆H₁₇N₅OS. EFFECT: detection of compounds showing activity indicated above. 2 tbl