(1,2,4-TRIAZINO-5,6-B-INDOLYL-3-THIO)-ACETIC ACID N-(2-HYDROXYETHYL)-AMIDE SHOWING ANTIHYPOXIC ACTIVITY AND RECOVERING FUNCTIONAL ELECTRIC BRAIN ACTIVITY

摘要

FIELD: organic chemistry. SUBSTANCE: product: (1,2,4-triazino-[5,6-b] -indolyl-3-thio)-acetic acid N-(2-hydroxyethyl)-amide of the formula . Empirical formula is C₁₃H₁₃N₅O₂S, yield is 67%, m. p. is 226 C. Reagent 1: 3-mercapto-1,2,4-triazino-[5,6-b]-indole. Reagent 2: N-(2-hydroxyethyl)-α-chloroacetamide. Reaction condition: in sodium hydroxide aqueous solution. EFFECT: improved method of synthesis. 2 tbl