首页> 外国专利> Use of a phagozytise - share four ends of substance: lps or il - 2 for the manufacture of a medicament for treatment of staphylococcus - aureus - infections in cows.

Use of a phagozytise - share four ends of substance: lps or il - 2 for the manufacture of a medicament for treatment of staphylococcus - aureus - infections in cows.

机译:吞噬酶的用途-共享物质的四个末端:lps或il-2用于制造用于治疗葡萄球菌-金黄色葡萄球菌-牛感染的药物。

摘要

The present invention relates to methods for treating infectious diseases in animals by initiating qualitative and quantitative changes in the phagocytic cells of said animals. This activation occurs by the administration of a phagocytic-cell activating agent, such as immunomodulators; cytokines such as inter­leukins (interleukin -1, 2, 3, 4, 5, 6 and 7), inter­ferons and colony stimulating factors; antimicrobials such as mucolytic enzymes, lysozyme, lysostaphin; complement and its components; chemotractants such as lipopolysaccharide and zymosan activated cow sera. The appropriate activation of the phagocytic cells in the animal for effective therapy requires not only an increase in the total number of cells which phagocytose cell particles, but also an increase in the number of particles phagocytosed per cell, intracellular killing. Thus, the present invention also relates to a method for measuring the efficiency of phagocytic-activating agents to predict and monitor appropriate therapy.
机译:本发明涉及通过启动所述动物的吞噬细胞的质和量变化来治疗动物传染病的方法。这种激活是通过吞噬细胞激活剂(例如免疫调节剂)的给药而发生的。细胞因子,例如白介素(白介素-1、2、3、4、5、6和7),干扰素和集落刺激因子;抗菌剂,例如粘液溶解酶,溶菌酶,溶葡萄球菌素;补体及其组成;趋化剂,例如脂多糖和酵母聚糖激活的牛血清。为了有效治疗动物中吞噬细胞的适当活化,不仅需要增加吞噬细胞颗粒的细胞总数,而且还需要增加每个细胞被吞噬的颗粒数目,从而杀死细胞。因此,本发明还涉及一种用于测量吞噬激活剂预测和监测适当疗法的效率的方法。

著录项

  • 公开/公告号DE69021791T2

    专利类型

  • 公开/公告日1996-05-02

    原文格式PDF

  • 申请/专利权人 AMERICAN CYANAMID CO US;

    申请/专利号DE1990621791T

  • 发明设计人 DALEY MICHAEL JOSEPH US;

    申请日1990-06-20

  • 分类号A61K38/00;

  • 国家 DE

  • 入库时间 2022-08-22 03:41:44

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号