MULTI-LAYER TABLETS WITH CONTROLLED DELIVERY OF ACTIVE SUBSTANCES CONTAINING BOTH NAPROXES AND NAPROXIC SODIUM SALT

摘要

The present invention relates to controlled release dosage forms composed of a naproxen layer which contains a delayed release granulate of naproxen compressed with an immediate release granulate of naproxen and an immediate release naproxen sodium layer compressed with the naproxen layer, designed to promptly exert a therapeutic effect while also maintaining the therapeutic blood concentration for a prolonged duration of 24 hours.