New derivatives descladinosyles of erythromycin, their process of preparation and their application as medicinal products.

摘要

The subject of the invention is the compounds of formula (I): IMAGE in which, - either X and X' form C=O or C=NOR with R=H, heterocycle, alkyl, alkenyl, alkynyl, optionally substituted, IMAGE Ra, Rb being a hydrocarbon radical or forming with the nitrogen atom a heterocycle, and X' = H, - Y and Y' have the same meaning as X and X', - B = H, OR4, R4 = H, or forms with A a carbonate or a carbamate, - A = OR'4, R'4 = H or forms with B a carbonate IMAGE n = integer from 1 to 6 R2 = alk or CONH2, CONHCOR11 or CONHSO2R11, R11, hydrocarbon up to 18c. IMAGE