Use of Tripterygium Wilfordii Hook F plant extracts and its components

摘要

Use of an extract of Tripterygium Wilfordii Hook F plant or one of its components in the treatment of human melanoma is new. Also claimed is the use of the above in the inhibition of mitogene-induced DNA synthesis, immunoglobulin synthesis and human melanoma cell proliferation. The component is pref. triptolide, triptodiolide, triptonide, polpunonic acid, methyl polpulonate, triptophenolide or its methyl ether, triptonoterpenol, wilformine, wilforine, wilforgine or wilforzine. The extract or component is diluted in a solution of poloxamer, pref. Pluronic F68NF (RTM) and is present in an amt. of 0.2-50 mg.