Deacetylcephalosporin C acetyltransferase from Acremonium chrysogenum

摘要

A DNA is disclosed, which comprises a gene coding for deacetylcephalosporin C acetyltransferase, i.e., an enzyme capable of catalyzing the final step of the biosynthesis of cephalosporin C. The gene may be either a cDNA or a genomic DNA. Also disclosed is a recombinant DNA comprising a vector having inserted therein at least a portion of the above-mentioned DNA, which recombinant DNA is in a form such that the portion is capable of expression in Acremonium chrysogenum. Acremonium chrysogenum transformed with the recombinant DNA can be advantageously used for efficiently preparing cephalosporin C.