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Process for the isolation and purification of ester functionalized imidazole intermediates by selective hydrolysis
Process for the isolation and purification of ester functionalized imidazole intermediates by selective hydrolysis
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机译:通过选择性水解分离和纯化酯官能化咪唑中间体的方法
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摘要
A method for isolating and purifying an ester functionalized imidazole compound, useful as an angiotensin (II) antagonist or as a key intermediate therefor, from a mixture of it with its regioisomer in a solvent, by treatment with an alkali metal hydroxide to achieve the regioselective hydrolysis of the undesired regioisomeric ester.
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