Method for distinguishing or monitoring the state of premalignant or malignant transformed human colonic tissue

摘要

The present application is directed to a method for distinguishing between normally differentiated and benign or malignantly transformed cells in human colonic tissue. It is also directed to a method for monitoring the state of premalignant or malignant human colonic tissue. In both methods, a 50F1 complementary DNA standard probe is utilized which hybridizes to the RNA in the test sample and to a second sample, which is a predetermined sample of colonic tissue, and the amount of hybridization of the 50F1 complementary DNA to the test sample is compared to the hybridization of the 50F1 complementary DNA with the second sample.