Test and model for poly cyst Characteristic ovarian syndromes and boy pattern alopecia

摘要

(57) Abstract As for poly cyst Characteristic ovarian (PCO) syndromes, it was discovered that it possesses the gene pathogenesis which becomes the root. Furthermore, with the man, revelation die of the disease was discovered, being the boy pattern alopecia (MPB). The mutation in the CYP17 gene which conveys the information of heredity of the P450c17 enzyme has validated the relationship of this revelation die. This mutation is the displacement 5 ' with the C of T inside the transcription field of this gene. On the basis of this kind of knowledge, the rearrangement DNA system for modelling, diagnosis, and remedy this disease is offered.