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Application use as an antioxidant of 2-mercapto-imidazole derivative which is substituted with (or 5) 4th, preparation method and pharmaceutical, to food industry or cosmetics
Application use as an antioxidant of 2-mercapto-imidazole derivative which is substituted with (or 5) 4th, preparation method and pharmaceutical, to food industry or cosmetics
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机译:被(或5)第4取代的2-巯基咪唑衍生物的抗氧化剂的制备方法和药物在食品工业或化妆品中的应用
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摘要
Use of 2-mercapto-imidazole derivs., substd. in position 4 or 5, of formula (I), as antioxidants, is new. R1, R2 = H, lower alkyl, or aralkyl (opt. substd.), provided that R1 or R2 = H; R3 = 0(CH2)nCOR4; -(CH2)nN+)R5R6R7),X-, -CH2CH(COR4)N+-(R5R6R7),X-; R4 = -OR8, -NHR5; - alpha -aminoacid (pref. natural), -NHCH2CH2SO3-,Y+ or (i) or (ii); R5,R6,R7,R8 = H, lower alkyl or aralkyl (opt. substd.); n = 1 or 2; X- = the anion of an acid and Y+ = the cation of a base, which are acceptable in cosmetics, pharmaceuticals and foodstuffs. (I) are new, provided that; (a) when R4 = -OR8, R1 andR2 are not both H; (b) when R1 and R2 are both H and when R4 = -OR8 then R5, R6, R7 are not all H; (c) when R3 = -CH2CH(COR4)N+)R5R6R7),X- and R4 = OH R5, R6, R7 are not all methyl.
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