The material which is produced from manner and its manner which produce the raw erosion Characteristic material for controlled release of the medicine

摘要

(57) Abstract It regards the material which is produced from manner and its manner which produce the raw erosion Characteristic material for controlled release of the medicine. This manner adjusts the density of the grain of the raw erosion Characteristic material in specified value, includes the fact that the raw erosion Characteristic material is mixed with the medicine of desire. And, the blend which is obtained, is pushed out to the configuration which is suited for internal burying planting, comminution in the grain for the application like inhalation delivery or the hypodermic injection. In a certain execution feature, the manner which forms in plant dissolves the erosion Characteristic living body material in the solvent, adjusting the density of the polymer by making freeze makes dry the solution which is obtained, includes specified porosity and the fact that the film of the raw erosion Characteristic polymer of density is formed. And, to fetch this film, comminution in low temperature, doing to screen, containment the grain of specified aperture distribution. It mixes these grains with the medicine of desire, comes after and it pushes out to the form which is desired the blend which is obtained to internal burying planting. Regarding another execution feature, the manner which adjusts density, dissolves the erosion Characteristic living body material in the solvent, it is the polymer solvent and miscibility, but the fact that it settles the polymer in the liquid which that polymer does not dissolve is included. Regarding another execution feature, the manner which mixes with the medicine and the polymer grain of desire, includes the ru thing which crushes the grain in the solution of the medicine which the grain does not dissolve. when the air is excluded including decompression, decompression is released, pushing in the solution into the pore in the blend with that, restoration substantially completely with the medicine it is possible the pore of the grain. Consequently when it makes freeze makes dry, although containment the medicine inside the pore, it is possible to remove the solvent.