NOVEL ISOXAZOLE DERIVATIVES, PROCESS FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

摘要

the invention relates to a new formula (i) u00e1ltalu00e1nu0151s izu0151xazu0151l - szu00e1rmazu00e9ku0151k, azelu0151u00e1llu00edtu00e1su0171kra szu0151lgu00e1lu00f3 procedure and form such hatu00f3anyagu0151t tartalmazu00f3gyu00f3gyu00e1szati preparations.in the formula (i) u00e1ltalu00e1nu0151s individually or in combination, and bjelentu00e9se hidru0151gu00e9natu0151m vegyu00e9rtu00e9kku00f6tu00e9s, z's report hidru0151gu00e9natu0151m, halu0151gu00e9natu0151m, 1 - 4 - methyl - szu00e9natu0151mu0151s alkilcsu0151pu0151rt, triflu0171u0151r csu0151pu0151rt,or one or two 1 - 4 szu00e9natu0151mu0151salku0151xicsu0151pu0151rt report, r1 and r2 independently of each other, szu00e9natu0151mu0151s alkilcsu0151pu0151rt 1 - 6, or 3 - 7 - szu00e9natu0151mu0151s ciklu0151alkilcsu0151pu0151rt, or r1 and r2 anitru0151gu00e9natu0151mmal,in which case, a kapcsu0151lu00f3dnak, and adu0151tt or tu00f6bbtu0151vu00e1bbi nitru0151gu00e9n - and / or u0151xigu00e9natu0151mmal together constitute a heteru0151ciklu0171su0151sgyu0171ru0171t of 5 to 8, which is 1 - 4 szu00e9natu0151mu0151s alkilcsu0151pu0151rttal,(1 - 4 - phenyl - csu0151pu0151rttal szu00e9natu0151mu0151salkil) (1 - 4 - phenyl - csu0151pu0151rttal szu00e9natu0151mu0151s alku0151xi), di (1 - 4 - phenyl - csu0151pu0151rttal szu00e9natu0151mu0151s alku0151xi), halu0151gu00e9n - phenyl - csu0151pu0151rttal,(triflu0171u0151r - methyl) - phenyl - or fu0171ru0151ilcsu0151pu0151rttal csu0151pu0151rttal lehethelyettesu00edtve value, m is 0 or 1, n is 0 or 1, with the condition of hu0151gy 1) if a and b vegyu00e9rtu00e9kku00f6tu00e9s report jointly.the value of m 0, tu0151vu00e1bbu00e1r1 and report each other as etilcsu0151pu0151rt r2 or r1 and r2 together with the anitru0151gu00e9natu0151mmal - which kapcsu0151lu00f3dnak - piperidin-1-yl - vagymu0151rfu0151linu0151 - csu0151pu0151rtu0151t constituteakku0151r z's report hidru0151gu00e9natu0151mtu00f3l u00e9spara favoured klu00f3ratu0151mtu00f3l different, and (2) if a and b vegyu00e9rtu00e9kku00f6tu00e9s report jointly, and r2 value of m 0, tu0151vu00e1bbu00e1r1 report each other as metilcsu0151pu0151rt,anitru0151gu00e9natu0151mmal or r1 and r2 together, to which kapcsu0151lu00f3dnak - pirru0151lidin - 1 - il - csu0151pu0151rtu0151t constitute, akku0151r z hidru0151gu00e9natu0151mtu00f3l meaning is different.in accordance with atalu00e1lmu00e1ny compounds linked to the nervous system or ku00f6zpu0151nti a1u00e9s / 5 - ht1a receptu0151ru0151khu0151z; pszichu0151tru00f3p and kardiu0151vaszku0171lu00e1rishatu00e1su0151kkal characteristics. a