首页> 外国专利> PROCESS FOR PRODUCING PIPERIDYLOXY AND QUINUCLIDINYLOXY ISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS

PROCESS FOR PRODUCING PIPERIDYLOXY AND QUINUCLIDINYLOXY ISOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS COMPRISING SUCH COMPOUNDS

机译:制备包含这种化合物的二羟基和半环状羟基异恶唑衍生物和药物组合物的方法

摘要

The present invention relates to novel piperidyl-oxy and kinylclidinyl-oxy-exoxy derivatives having the general formula (I) wherein R1 is hydrogen or halo or alkyl; R 2 is hydrogen; alkyl; substituted phenyl ring in the case of at least one of the substituents (a); or 2-thienyl or 3-pyridyl; or R 1 and R 2 together (XIII) are generic pellets and R 4, R 5, R 6, and R 7 are independently hydrogen or halo or alkyl, alkyloxy, pyrethylmethyl, and R 3 are piperidyl, pelletized with nitro-gyropathyl; or a non-disubstituted kinetic clidin-cholesterol, (a) a typhoid gene or a trifluoro-methyl tube. The compounds of general formula (I) can be used to prevent the treatment of stomach disorders, first and foremost of old-fashioned mental illness, including Alzheimer's disease. ŕ
机译:本发明涉及具有通式(Ⅰ)的新颖的哌啶基-氧基和缩水甘油基-氧基-过氧基衍生物,其中R 1为氢或卤素或烷基。 R 2为氢;烷基;在至少一个取代基(a)的情况下取代的苯环;或2-噻吩基或3-吡啶基;或或R 1和R 2一起(XIII)是通用粒料,并且R 4,R 5,R 6和R 7独立地是氢或卤素或烷基,烷氧基,吡乙基甲基,并且R 3是哌啶基,并用硝基回转体造粒。或非二取代的动力学克林蛋白-胆固醇,(a)伤寒基因或三氟甲基管。通式(I)的化合物可用于预防胃部疾病的治疗,首先是最主要的老式精神疾病,包括阿尔茨海默氏病。 ŕ

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