1-AND 2-SUBSTITUTED 1H-IMIDAZO4,5-CQUINOLIN-4-(SUBSTITUTED) DERIVATIVES FOR PRODUCING 1-AND 2-SUBSTITUTE 1H-IMIDAZO4,5-CQUINOLIN-4-AMINE DERIVATIVES

摘要

Intermediates for preparing 1-substituted, 2-substituted 1H-imidazo Ä4,5-cÜ-quinolin-4-amines of formula (I) are provided where X is selected from the group consisting of alkoxy, alkoxyalkyl, haloalkyl, hydroxyalkyl, alkylamido, amino or substituted amino wherein the substituent is alkyl, hydroxyalkyl, azido, chloro, hydroxy, 1-morpholino, 1-pyrrolidino, and alkylthio. The compounds of formula (I) function as antiviral agents, they induce biosynthesis of interferon, and they inhibit tumor formation in animal models. CHEM