1-AND 2-SUBSTITUTED 1H-IMIDAZO4,5-CQUINOLIN-4-(SUBSTITUTED) DERIVATIVES FOR PRODUCING 1-AND 2-SUBSTITUTE 1H-IMIDAZO4,5-CQUINOLIN-4-AMINE DERIVATIVES

摘要

The present invention relates to compounds of formula XIa wherein R5 is linear or branched (C1-C6) -alkyl, (C1-C4) -alkoxy (C1-C6-alkyl), benzyl or phenylethyl; R 2 and R 3 are independently hydrogen, C 1-4 alkyl, or phenyl; Z is C 1-4 alkoxy, C 1-6 alkanoyloxy, hydroxy or benzoyloxy; Q is hydrogen or chlorine; R is hydrogen, provided that when Z is hydroxy, R5 is (C1 -C4) alkoxy (C1 -C6) alkyl. The compounds of the invention are useful as intermediates in the preparation of 1-imidazo [4,5-c] quinolin-4-amines substituted at the 1- and 2-positions. ŕ