The Invention relates to the modification of the Crystalline hydrochloride of compound V (R) - (-) - 2 - {n - [4 - (1,1 dioxide - 3 - oxo 2,3 dihydro - - 2 - - benzisotiazol il) butyl] - Aminomethyl - chromane},Formula (i) which is stable at Ambient temperature.The modification is apropiadaespecialmente hydrochloride Crystalline V for the preparation of Solid Drugs, especially drugs for the treatment of neuronal Degeneration.The invencionse also refers to the process for preparing Said hydrochloride, medicines that contain, the use thereof for preparing dichosmedicamentos,A composition for the treatment and Prevention of neuronal Degeneration due to Ischemic Events and a method to try and prevent these degenerations.
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