fluidisisällöllä steriloitavan pre filled syringes filling and sulkemismenetelmä

摘要

PCT No. PCT/DE95/01523 Sec. 371 Date Jun. 19, 1997 Sec. 102(e) Date Jun. 19, 1997 PCT Filed Oct. 27, 1995 PCT Pub. No. WO96/13289 PCT Pub. Date May 9, 1996A process for filling and sealing a fluid-containing plastic disposable syringe that is to be sterilized, wherein the disposable syringe includes a barrel having a front end, a nozzle part having a sealing element, a plunger plug, and a plunger stop element that is placed in the area of a cylinder gripping plate, the process includes inserting and pushing the plunger plug into the front end of the barrel, using pressure and forcing a fluid medium into the barrel via the nozzle part, whereby the fluid medium pushes the plunger plug in the direction of the plunger stop element, and sealing the sealing element of the nozzle part by plastic deformation after the barrel and the nozzle part are filled.