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COUNTERING THE ADVERSE EFFECTS OF AGING ON MAMMALIAN CELLS USING 6-(SUBSTITUTED AMINO) PURINE CYTOKININS
COUNTERING THE ADVERSE EFFECTS OF AGING ON MAMMALIAN CELLS USING 6-(SUBSTITUTED AMINO) PURINE CYTOKININS
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机译:用6-(取代的氨基酸)嘌呤细胞分裂素对抗衰老对哺乳动物细胞的不利影响
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摘要
Ameliorating the adverse effects of ageing on mammalian cells comprises; contacting the cells with a compsn. that contains a 6-(substd. amino) purine cytokinin in a concn. sufficient to ameliorate the adverse effects of ageing. The rate of development of characteristics of ageing is reversed or slowed, and the growth rate and total proliferative capacity of the cells, after contact with the compsn., is the same as prior to contact. Pref. the cytokinin is of formula (I). In (I) R1 = furfuryl, phenyl, benzyl, 4-6C n-alkyl, cyclohexylmethyl, (3-hydroxymethyl-3-methyl)allyl or 3,3-dimethylallyl. (I) is most esp. furfuryladenine (kinetin).
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