DNA ENCODING C100-R (RECEPTOR FOR THE BETA-AMYLOID PRECURSOR PROTEIN) ITS PRODUCTION USING ENGINEERING HOST CELLS AND ITS USE IN IDENTIFYING C100 LIGAND ANTAGONISTS

摘要

The present invention relates to the cloning of beta APP-C100 receptor (C100-R), and genetically engineered host cells which express the C100-R. Such engineered cells may be used to evaluate and screen drugs and analogs of beta -APP involved in Alzheimer's Disease.