首页> 外国专利> AGENT FOR INTENSIFYING THE PROCESS OF SUPPLYING OXYGEN TO SKIN, USED IN DERMATOLOGICA PREPARATIONS AND METHOD OF OBTAINING SUCH AGENT

AGENT FOR INTENSIFYING THE PROCESS OF SUPPLYING OXYGEN TO SKIN, USED IN DERMATOLOGICA PREPARATIONS AND METHOD OF OBTAINING SUCH AGENT

机译:皮肤制剂中使用的用于增强向皮肤供氧的方法的代理商和获得此类代理商的方法

摘要

PCT No. PCT/DE93/00572 Sec. 371 Date Dec. 22, 1994 Sec. 102(e) Date Dec. 22, 1994 PCT Filed Jun. 24, 1993 PCT Pub. No. WO94/00109 PCT Pub. Date Jan. 6, 1994The invention relates to a dermatological agent for assisting the transport of oxygen in the skin, a process for its preparation and the use thereof. The problem with the known dermatological agents is the inadequate supply of oxygen to the skin and the adjoining tissue. The object of the invention is therefore to get through the horny layer of the skin and the epidermis by penetration processes in order to increase the oxygen concentration in the dermal area and adjoining tissue and to activate metabolic processes. According to the invention, this is effected by means of a dermatological agent containing asymmetric lamellar aggregates, consisting of phospholipids and oxygen-laden fluorocarbon or fluorocarbon mixture, the amount of fluorocarbon being in the range from 0.2 to 100% weight/volume, in a carrier which is suitable for dermatological use. Preparation is effected by emulsification of the corresponding constituents, and use in ointments, creams, lotions, waters, alcoholic extracts, pastes, powders, gels, tinctures or on dressings and plasters or in a spray.
机译:PCT号PCT / DE93 / 00572秒371日期1994年12月22日102(e)日期,1994年12月22日,PCT,1993年6月24日提交,PCT Pub。 WO94 / 00109 PCT公开号1994年1月6日,本发明涉及用于辅助氧气在皮肤中运输的皮肤病学试剂,其制备方法及其用途。已知的皮肤病学试剂的问题是对皮肤和邻接组织的氧气供应不足。因此,本发明的目的是通过渗透过程穿过皮肤和表皮的角质层,以增加皮肤区域和邻接组织中的氧浓度并激活代谢过程。根据本发明,这是通过含有不对称的层状聚集体的皮肤病学试剂来实现的,该不对称的层状聚集体由磷脂和含氧的碳氟化合物或碳氟化合物混合物组成,碳氟化合物的量在0.2至100%重量/体积的范围内。适用于皮肤病学的载体。通过乳化相应成分来进行制备,并将其用于软膏剂,乳膏剂,洗剂,水,酒精提取物,糊剂,粉剂,凝胶剂,s剂中或在敷料和灰泥上或以喷雾剂的形式使用。

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