METHOD OF OBTAINING HIGHLY PURIFIED, PROTECTED AGAINST VIRUSES VIII FACTOR PREPARATION

摘要

The invention relates to a process for the preparation of a highly purified, virus-safe factor VIII preparation, characterised by combination of the following measures a) a chromatographic purification of a factor VIII-containing fraction, b) a surfactant treatment of the factor VIII in aqueous solution with a surfactant/protein ratio of 1:1 to 66:1 and c) a heat treatment of the factor VIII preparation in the solid state.