NOVEL METHOD OF ISOLATING CLAVULANIC ACIDS AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF FROM FERMENTATION BROTH OF STREPTOMYCES SP. P 6621 FERM P 2804

摘要

A process for the isolation of clavulanic acid pharmaceutically acceptable salts thereof, such as potassium clavulanate, from the aqueous fermentation broth of a clavulanic acid-producing microogranism comprises the microfiltration of the broth without prior treatment.