procedures for the specific removal of saliva alpha amylase and determination of pancreatic alpha amylase

摘要

Inter alia, a process for the selective removal of salivary alpha -amylase from a sample comprising salivary alpha -amylase and pancreatic alpha -amylase characterised in that there is used a monoclonal antibody against salivary alpha -amylase, which is immobilised or is coupled to a physically seperable or seperate support and which exhibits a binding affinity towards salivary alpha -amylase of at elast 1 x 107 l/m and a cross-reactivity with pancreatic alpha -amylase of less than 1% is disclosed. The remaining pancreatic alpha -amylase may be assayed.