IMMUNOLOGICALLY ACTIVE PROTEINS OF BORRELIA BURGDORFERI, RELATED TEST KITS AND VACCINE.

摘要

BORRELIA BURGDORFERI ACTIVE IMMUNOLOGICAL PROTEINS, RELATED TEST KITS AND VACCINES. VARIOUS IMMUNOLOGICALLY ACTIVE PROTEINS OF BORRELIA BURGDORFERI WERE PRODUCED IN MICROORGANISMS BY TECHNOLOGICAL TREATMENT OF GENES. FOR THIS, THE SPECIFIC DNA SEQUENCES OF A B. BURGDORFERI GENE BANK WERE SELECTED WITH APPROPRIATE SEARCH METHODS AND REPRESENTED DIRECTLY THROUGH THE AMPLIFICATION OF DNA WITH SELECTED PROMOTOR PROBLEMS AND BY PROMOTORS. LAC. THROUGH THE DESCRIPTION OF EFFICIENT CLEANING PROCEDURES FOR SQUEEZED ANTIGENS, PROTEINS COULD BE DISPOSED IN THE PROPER WAY. WITH THESE PROTEINS, SPECIFIC AND SENSITIVE DIAGNOSTIC TEST KITS CAN BE MADE. THROUGH THE SELECTIVE COMBINATION OF ACTIVE PROTEINS IMMUNOLOGICALLY, A PRECISE DIAGNOSIS IS POSSIBLE. FURTHER, MONOCLONAL ANTIBODIES WERE GENERATED, WHICH ARE FOUND APPLICATION AS REACTANTS FOR THE EXCITATION TEST DIRECTLY OF EXAMINATION TESTS AND AFTER THE CULTIVATION. THE SPECIFIC DNA SEQUENCES OF BORRELIA BURGDORFERI MAY BE APPLIED IN PATIENT TESTS FOR DIRECT DEMONSTRATION OF THE EXCITANT (eg, THROUGH PCR REACTION).