Transferrin-binding protein 1 (Tbp1) gene of Actinobacillus pleuropneumoniae, its use in vaccines for pleuropneumonia and as diagnostic reagents

摘要

The present invention relates to the gene of transferrin-binding protein 1 (Tbp1) of Actinobacillus pleuropneumoniae, its use to prepare products for vaccination against porcine pleuropneumonia or as diagnostic reagents. The invention also relates to the use of Tbp1 or fragments thereof to produce monoclonal or polyclonal antibodies to be used as diagnostic reagents. The invention also relates to the use of Tbp1 or fragments thereof, alone or combined to other virulence factors of the pathogen, as vaccination products against porcine pleuropneumonia.