Regulation of the recombination site-specific recombinase fusion proteins by site-specific / nuclear receptor.

摘要

It DESCRIBED an invention that allows adjustment recombinant cells, organisms or cell-free SYSTEMS SUITABLE. THE invention to provide fusion proteins between recombinase PROTEIN OR recombinase system components, and ligands links fields RESULTING FROM NUCLEAR RECEPTORS. FUSION PROTEIN show a small recombinase activity in the absence of ligand binds to the ligand binding FIELD. By linking the ligand, recombinase ACTIVITY REDUCE.LA invention provides a means PRACTICAL TO REGULATE Recombination in cells and organisms, ENLAZANDO ligand binding recombination is provided a simple means bringing the ligand binding MAY BE Recombination REALIZED AS MEASURED.