TARGET CELL-SPECIFIC VECTORS FOR INSERTING GENES INTO CELLS,PHARMACEUTICALS COMPRISING SUCH VECTORS AND THEIR USE

摘要

Target cell-specific vectors for inserting genes into cells, pharmaceuticals comprising such vectors and their use Target cell-specific vectors for inserting at least one gene into cells of an organism, which vectors comprise the following components: a) a non-viral carrier for the gene to be inserted, b) a ligand which can bind specifically to the desired target cell, c) a fusion protein for the penetration of the vector into the cytoplasm of the target cell, and d) the gene to be introduced are disclosed. Vectors of this nature are used, in particular, in gene therapy.