A family of organic anion transporters, nucleic acids encoding them, cells comprising them and methods for using them

摘要

The present invention provides a novel family of organic anion transporters of which until now only one member was known. The family includes multispecific organic anion transporters related to the canalicular multispecific organic anion transporter. The cDNA encoding the latter is also provided. The rat and human cDNA are exemplified. Uses of nucleic acids based on this gene family and of cells comprising such nucleic acids as well as vectors comprising sequences thereof are also disclosed especially in the area of gene therapy.