Manipulation of mitotically active cells of the hippocampal region of the brain

摘要

A method is disclosed for the in vivo proliferation of a multipotent neural stem cell located in the hippocampal region of a mammal. The method comprises administering at least one growth factor to the hippocampal region which induces the proliferation of the stem cell to produce stem cell progeny that are capable of differentiating into neurons and glial cells. The method provides treatments for neurological diseases, injuries, or disorders which affect the hippocampal region of the brain, such as stroke.