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Novel heterocyclic compounds having platelet aggregation inhibitory effects

机译:具有抑制血小板聚集作用的新型杂环化合物

摘要

Disclosed are a compound represented by the following formula (I) and pharmacologically acceptable salt and solvate thereof having inhibitory activity against platelet aggregation: CHEM wherein A represents the following formula (II), (III), or (IV): CHEM A pharmaceutical composition comprising the above compound can be utilized as a platelet aggregation inhibitor that possesses excellent inhibitory activity against platelet aggregation, is free from hemorrhage and other side effects such as those derived from selectivity for the inhibitory action, and is potent against vasculature lesions, such as vasospasm.
机译:公开了由下式(I)表示的化合物及其对血小板凝集具有抑制活性的药理学上可接受的盐和溶剂化物:其中A表示下式(II),(III)或(IV):包含上述化合物的药物组合物可用作血小板凝集抑制剂,其对血小板凝集具有优异的抑制活性,没有出血和其他副作用,例如源自抑制作用的选择性,并且对脉管系统病变有效,例如血管痉挛。

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