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Novel antiproliferative protein from bacillus thuringiensis var. thuringiensis
Novel antiproliferative protein from bacillus thuringiensis var. thuringiensis
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机译:苏云金芽孢杆菌变种的新型抗增殖蛋白苏云金
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摘要
The present invention provides an isolated and purified protein derived from Bacillus thuringiensis subspecies thuringiensis, having a molecular weight of approximately 20 kDa of SDS-PAGE, said protein having the partial amino acid sequence shown in SEQ ID No. 1, and wherein said protein displays cytotoxic effects against tumor cells. Also provided is a method of treating a neoplastic cell comprising administering a therapeutically effective dose of the composition of the present invention to said cell.
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机译:本发明提供了分离纯化的来自苏云金芽胞杆菌亚种苏云金芽孢杆菌的蛋白质,其分子量约为20kDa的SDS-PAGE,所述蛋白质具有SEQ ID No.1所示的部分氨基酸序列,并且其中所述蛋白质展示对肿瘤细胞的细胞毒性作用。还提供了一种治疗赘生性细胞的方法,该方法包括向所述细胞施用治疗有效剂量的本发明的组合物。
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