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Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease
Method of allogeneic hematopoietic stem cell transplantation without graft failure or graft vs. host disease
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机译:没有移植失败或移植物抗宿主病的同种异体造血干细胞移植方法
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摘要
The present invention provides a method of transplanting hematopoietic system reconstituting cells from a donor into an allogeneic recipient comprising administering to the recipient, prior to the administration of the hematopoietic system reconstituting cells, an amount of mononuclear cells which are treated so as to render them incapable of proliferating and causing a lethal graft versus host disease effect, but which are effective in enhancing subsequent engraftment of the hematopoietic system reconstituting cells in the recipient; and administering to the recipient an effective amount of hematopoietic system reconstituting cells.
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